An evaluation of available scientific information found that some uses of thiamethoxam products meet current standards for protection of aquatic invertebrate communities when used according to the revised conditions of registration, which include required amendments to label directions. Label amendments, as summarized below and listed in Appendix VIII of SRD2021-04, are required for all end-use products. Certain uses of thiamethoxam are cancelled as risks to aquatic invertebrates were not shown to be acceptable.