Effects of brominated emerging flame retardants in juvenile rainbow trout

In this study, the chronic effects of two emerging brominated flame retardants, 1,2-bis(2,4,6-tribromophenoxy)ethane(BTBPE) and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB) were evaluated in diet exposed juvenile rainbow trout(Oncorhynchus mykiss). FIsh uptake was measured after 28-d of exposure. Liver gene transcription analysis using RNA-sequencing was also performed, complemented by qRT-PCR to measure transcription levels of genes related to the immune response in the liver and the head kidney. Lysozyme enzymatic activity was also measured in head kidneys of exposed fish. Results were published in a peer-reviewed scientific publication that can be found here: https://doi.org/10.1016/j.aquatox.2017.02.023

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Title (French)	Effets de retardateurs de flammes émergent chez la truite arc-en-ciel juvénile
Update Frequency	as_needed
Geographic Scope	["2466"]
Criticality Level	[]
Sensitivity Level	unrestricted
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Open Canada Date Published	2021-11-05 00:00:00
Open Canada Date Modified
Open Canada Subject	["nature_and_environment"]
Open Canada Keywords	{"fr": ["Toxicologie", "toxique", "Poisson d'eau douce", "Poisson", "Biologie", "Génomique", "Chimie", "Animal aquatique", "truite arc-en-ciel", "retardateurs de flamme", "BTBPE", "EHTBB", "réponse immunitaire", "lysozyme", "séquençage de l'ARN", "L'initiative de recherche en génomique (IRDG)", "applications stratégiques des technologies génomiques dans le domaine de l'environnement (STAGE)", "Plan de Gestion des Produits Chimiques (PGPC)", "transcription de gènes", "toxicité chronique", "exposition par la nourriture"], "en": ["Toxicology", "Toxic substances", "Freshwater fish", "Fish", "Biology", "Genomics", "Chemistry", "Aquatic animals", "rainbow trout", "flame retardants", "BTBPE", "EHTBB", "immune response", "lysozyme", "RNA-sequencing", "Genomics R&D Initiative (GRDI)", "Strategic Technology Applications of Genomics in the Environment (STAGE)", "Chemical Management Plan (CMP)", "gene transcription", "chronic toxicity", "food-borne exposure"]}
Open Canada Collection	primary
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