Regional-scale thrust faults in the Klondike District separate major lithologic units that include medium-grade metamorphic rocks of the Upper Permian Klondike Schist and middle to late Paleozoic Finlayson (Nasina) assemblage, as well as relatively low-grade greenstone and ultramafic rocks of the Slide Mountain terrane. These units were emplaced in the Jurassic as a series of kilometre-scale stacked thrust slices that are locally separated by additional ultramafic slices. A distinctive set of post-metamorphic compressional structures related to thrusting, particularly a set of ductile recumbent folds and associated spaced cleavage, is preserved in all thrust slices and is well developed near bounding faults. In carbonaceous units within the Klondike Schist, spatially associated with some thrusts, carbonaceous material is locally concentrated along the thrust-related spaced cleavage. Thrust-related fabrics are overprinted by kink-folding that locally affects the Finlayson assemblage, but is mainly developed in Klondike Schist. Gold-bearing veins appear confined to Klondike Schist and were emplaced in local sites of extension controlled principally by axial surfaces of these kink folds.